Disruption of a molecular pathway may be involved in Alzheimer’s
Disruption of a specific molecular pathway may lead to the degeneration seen in late-onset Alzheimer’s disease, the non-familial and most common form of the disorder. A team headed by NIA scientists found when a signaling pathway called ApoER2-Dab1 malfunctions in human brain neurons, the neurons accumulate phosphorylated tau — the form that leads to tau…